THRIVE aims to dramatically reduce mortality among adults and children living with HIV by enabling access to critical prevention, screening, and treatment commodities, and centering local leadership and community-owned solutions to find and serve people living with AHD where they are.
This work is made possible with the support of Unitaid through the Clinton Health Access Initiative-led THRIVE project in partnership with Afrocab and Penta.
In September 2025, a mother brought her young child to Mkoba Polyclinic with severe acute malnutrition, significant weight loss, poor feeding, oral thrush, and a swollen abdomen. Born outside a health facility in March 2024, the child had missed early infant HIV diagnosis and the opportunity for timely treatment. Clinical testing confirmed that both mother and child were living with HIV, while further investigation revealed that the child also had tuberculosis (TB).
Starting treatment for advanced HIV disease (AHD) is a critical first step, but outcomes depend on whether people can stay on treatment. Under the Unitaid-funded THRIVE project, led by CHAI in partnership with AFROCAB and Penta, AFROCAB AHD Champions in Zimbabwe support people through the period after diagnosis, when the risk of falling out of care is high. The stories of Linnet and Memory show what that support looks like in practice.
Today is World Food Day, a reminder that access to adequate nutrition is fundamental to health and survival. For children with advanced HIV disease (AHD), the stakes are particularly high.
"By deepening collaboration, expanding the scope of work, and embracing innovation, there is hope that the target of ending AIDS by 2030 remains within reach. The work continues, and the world must remain united in this essential mission."
Dr. Nathan Ford
Scientific Officer, WHO
AHD Alliance co-chair
This work was made possible with the support of Unitaid through the Clinton Health Access Initiative-led THRIVE project in partnership with Afrocab and Penta